{"id":713,"date":"2019-06-10T09:32:28","date_gmt":"2019-06-10T07:32:28","guid":{"rendered":"http:\/\/konferencia.uef.sav.sk\/?page_id=713"},"modified":"2019-06-14T00:50:07","modified_gmt":"2019-06-13T22:50:07","slug":"poster-presentations","status":"publish","type":"page","link":"http:\/\/konferencia.uef.sav.sk\/?page_id=713","title":{"rendered":"Poster presentations"},"content":{"rendered":"<table>\n<tbody>\n<tr>\n<td colspan=\"2\" width=\"803\">\n<h4><strong>Ecotoxicology<\/strong><\/h4>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-1<\/strong><\/td>\n<td width=\"732\">ENVIRONMENTAL OCCURRENCE AND TOXICITY OF ORGANIC UV FILTERS<\/p>\n<p>Cahov\u00e1 J.<sup>1<\/sup>, Blahov\u00e1 J.<sup>1<\/sup>, Svobodov\u00e1 Z.<sup>1<\/sup><\/p>\n<p><sup>1 <\/sup>Department of Animal Protection, Welfare and Behaviour, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno,&nbsp; Czech republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-2<\/strong><\/td>\n<td width=\"732\">Aquatic ecosystems comparison from the point of view of heavy metals pollution<\/p>\n<p>Dvo\u0159\u00e1k P.<sup>1<\/sup>, Andreji J.<sup>2<\/sup>, Dvo\u0159\u00e1kov\u00e1 L\u00ed\u0161kov\u00e1 Z.<sup>3<\/sup>, Roy K.<sup>1<\/sup>, Mr\u00e1z J.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>&nbsp;University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Institute of Aquaculture and Protection of waters, Ceske Budejovice, Czech Republic;&nbsp;<sup>2<\/sup>&nbsp;Department of Poultry Science and Small Farm Animals, Slovak University of Agriculture, Nitra, Slovak Republic;&nbsp;<sup>3<\/sup>Faculty of Economy, University of South Bohemia, Ceske Budejovice, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-3<\/strong><\/td>\n<td width=\"732\">Study of the impact of silver nanoparticles on representatives of soil fauna<\/p>\n<p>Hlavkova D., Havelkova B., Beklova M.<\/p>\n<p>Department of Ecology and Diseases of Game, Fish and Bees, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-4<\/strong><\/td>\n<td width=\"732\">THE EFFECTS OF MICROPLASTICS ON RAINBOW TROUT (ONCORHYNCHUS MYKISS)&nbsp;<\/p>\n<p>Hodkovicova N.<sup>1,2<\/sup>, Minarova H.<sup>2,3<\/sup>, Caloudova H.<sup>1<\/sup>, Faldyna M.<sup>2<\/sup>, Marsalek P.<sup>1<\/sup>, Svobodova Z.<sup>1&nbsp;<\/sup><\/p>\n<p><sup>1<\/sup>University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Veterinary Hygiene and Ecology, Department of Animal Protection, Welfare and Behaviour, Brno, Czech Republic; <sup>2<\/sup> Veterinary Research Institute, Department of Immunology, Brno, Czech Republic; <sup>3<\/sup> University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Veterinary Hygiene and Ecology, Department of Ecology and Diseases of Game, Fish and Bees, Brno, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-5<\/strong><\/td>\n<td width=\"732\">NOTHOBRANCHIUS FURZERI AND TRIPLOID FORM DANIO RERIO AS A MODEL ORGANISMS FOR ENDOCRINE POLUTANTS TESTING IN WATER TOXICOLOGY<\/p>\n<p>Koutkov\u00e1 Z., Svobodov\u00e1 Z.<\/p>\n<p>Unviersity of Veterinary and Pharmaceutical Sciencis Brno, Institute Animal Protection and Welfare, Department Veterinary Toxikology and Toxikology of Foodstuff, Brno, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-6<\/strong><\/td>\n<td width=\"732\">2-D Electrophoresis as a Tool for Determination the Markers of Acute Toxicity in Pancreatic Beta Cells Exposed to a Lethal Dose of the Organochlorine Pesticide DDT<\/p>\n<p>Pavlikova N.<sup>1<\/sup>, Sramek J.<sup>1<\/sup>, Jelinek M.<sup>1<\/sup>, Halada P.<sup>2<\/sup>, Kovar J.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Department of Cellular and Molecular Biology, Third Faculty of Medicine, Charles University, Prague, Czech Republic; <sup>2<\/sup>Laboratory of Molecular Structure Characterization, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-7<\/strong><\/td>\n<td width=\"732\">FORMETANATE ADVERSE EFFECTS ON DEVELOPMENTAL STAGES OF HONEYBEES<\/p>\n<p>Sabo R., Sabov\u00e1 L., Leg\u00e1th J.<\/p>\n<p>Department of Pharmacology and Toxicology, University of Veterinary Medicine and Pharmacy in Kosice, Komensk\u00e9ho 73, 041 81 Ko\u0161ice, Slovakia<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-8<\/strong><\/td>\n<td width=\"732\">Effect of antidepressant sertraline on rainbow trout<\/p>\n<p>V\u00e1clav\u00edk J., Svobodov\u00e1 Z.<\/p>\n<p>Veterinary and Pharmaceutical University Brno, Palack\u00e9ho t\u0159\u00edda 1946\/1, 61242, Brno, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"803\">\n<h4>&nbsp;<\/h4>\n<h4><strong>Developmental Toxicology<\/strong><\/h4>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-9<\/strong><\/td>\n<td width=\"732\">Clinical consequences of most frequent trisomies on postnatal neonatal adaptation<\/p>\n<p>Brucknerov\u00e1 I.<sup>1<\/sup>, Laba\u0161kov\u00e1 S.<sup> 2<\/sup>, Brucknerov\u00e1 J.<sup>2<\/sup>, Dubovick\u00fd M.<sup>3<\/sup>, Ujh\u00e1zy E.<sup>3<\/sup><\/p>\n<p><sup>1<\/sup>Neonatal Department of&nbsp; Intensive Medicine, Faculty of Medicine, Comenius University in Bratislava, Libova 1, Bratislava, Slovakia; <sup>2<\/sup>Faculty of Medicine, Comenius University in Bratislava, \u0160pitalsk\u00e1 24, Bratislava, Slovakia; <sup>3<\/sup>Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, D\u00fabravsk\u00e1 cesta 9, Bratislava, Slovakia<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-10<\/strong><\/td>\n<td width=\"732\">Effects of bupropion administration during pregnancy and lactation on maternal behavior and selected reproductive variables in rats<\/p>\n<p>Csatlosova K.<sup>1,2<\/sup>, Simoncicova E.<sup>1,2<\/sup>, B\u00f6gi E.<sup>1<\/sup>, Dubovicky M.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Institute of Experimental Pharmacology and Toxicology, Centre of Experimental Medicine of the Slovak Academy of Sciences, Bratislava, Slovak Republic; <sup>2<\/sup>Department of Pharmacology, Jessenius Faculty of Medicine, Comenius University, Martin, Slovak Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-11<\/strong><\/td>\n<td width=\"732\">The effect of prenatal and early postnatal exposure to phthalate mixture on anxiety-like and depression-like behaviour in rats<\/p>\n<p>Morov\u00e1 M., \u0160tefunkov\u00e1 M., Senko T., Olexov\u00e1 L., Kr\u0161kov\u00e1 L.<\/p>\n<p>Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University in Bratislava, Slovakia<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-12<\/strong><\/td>\n<td width=\"732\">Impact of prenatal hypoxia on neurotransmitter systems in the rat brain<\/p>\n<p>Pie\u0161ov\u00e1 M.<sup>1,2<\/sup>, Koprdov\u00e1 R.<sup>1<\/sup>, Hadov\u00e1 K.<sup>3<\/sup>, K\u0159enek P.<sup>3<\/sup>, Mach M.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Institute of Experimental Pharmacology and Toxicology, Centre of Experimental Medicine, Slovak Academy of Sciences, Bratislava, Slovakia; <sup>2<\/sup>Jessenius Faculty of Medicine in Martin, Comenius University, Bratislava, Slovakia; <sup>3<\/sup>Faculty of Pharmacy, Comenius University, Bratislava, Slovakia<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-13<\/strong><\/td>\n<td width=\"732\">COMPARISON OF EMBRYOTOXIC EFFECTS OF VENOMS IN SELECTED AFRICAN AND ASIAN SNAKE SPECIES OF THE GENUS NAJA<\/p>\n<p>Poll\u00e1kov\u00e1 M.<sup>1<\/sup>, Andrej\u010d\u00e1kov\u00e1 Z.<sup>1<\/sup>, Petrilla V.<sup>1<\/sup>, Ondra\u0161ovi\u010dov\u00e1 S.<sup>1<\/sup>, Vl\u010dkov\u00e1 R.<sup>1<\/sup>, Petrillov\u00e1 M.<sup>2<\/sup>, Sopkov\u00e1 D.<sup>1<\/sup><\/p>\n<p>The University of Veterinary Medicine and Pharmacy in Kosice, Department of Physiology, Ko\u0161ice, Slovakia; The University of Veterinary Medicine and Pharmacy in Kosice, Department of General Education Subjects, Ko\u0161ice, Slovakia;<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-14<\/strong><\/td>\n<td width=\"732\">EFFECT OF PRE-GESTATIONAL STRESS AND VENLAFAXINE TREATMENT ON HIPPOCAMPAL SYNAPTIC STRUCTURE IN RAT OFFSPRING<\/p>\n<p>Simoncicova E.<sup>1,2<\/sup>, Belovicova K.<sup>1<\/sup>, Csatlosova&nbsp;K.<sup>1,2<\/sup>, Dubovicky M.<sup>1<\/sup>, Bogi E.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Institute of Experimental Pharmacology and Toxicology, Centre of Experimental Medicine of the Slovak Academy of Sciences, Bratislava, Slovak Republic; <sup>2<\/sup>Department of Pharmacology, Jessenius Faculty of Medicine, Comenius University, Martin, Slovak Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-15<\/strong><\/td>\n<td width=\"732\">Evaluation of the effects of a standardized Cynara cardunculus leaf extract on prenatal Rat development<\/p>\n<p>Ujhazy E.<sup>1<\/sup>, Farkas M.<sup>1<\/sup>, Koprdova R.<sup>1<\/sup>, Nagy M.<sup>2<\/sup>, Mucaji P.<sup>2<\/sup>, Brucknerova I.<sup>3<\/sup>, Mach M.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Centre of Experimental Medicine of the Slovak Academy of Sciences, Institute of Experimental Pharmacology and Toxicology, Bratislava, Slovakia; <sup>2<\/sup>Faculty of Pharmacy, Comenius University in Bratislava, Department of Pharmacognosy and Botany, Bratislava, Slovakia; <sup>3<\/sup>Neonatal Department of Intensive Medicine, Faculty of Medicine, Commenius University&nbsp; and National Institute of Children\u00b4s Diseases, Bratislava, Slovakia<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"803\">\n<h4>&nbsp;<\/h4>\n<h4><strong>Veterinary Toxicology<\/strong><\/h4>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-16<\/strong><\/td>\n<td width=\"732\">THE CASE OF PIG POISONING BY THE PESTICIDE PRODUCT REGLONE (DIQUAT)<\/p>\n<p>\u0160irok\u00e1 Z.<sup>1<\/sup>, Svoboda M.<sup>2<\/sup>, N\u00e1gl I.<sup>3<\/sup><\/p>\n<p><sup>1 <\/sup>Department of Animal Protection, Welfare and Behaviour, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic, <sup>2<\/sup> Ruminant and Swine Clinic, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic, <sup>3<\/sup> State Veterinary Institute Praha, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"803\">\n<h4>&nbsp;<\/h4>\n<h4><strong>Immunotoxicology<\/strong><\/h4>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-17<\/strong><\/td>\n<td width=\"732\">ENZYMATIC DESIALYLATION OF LUNG EPITHELIUM INCREASES BINDING OF LECTIN PAIIL, PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR<\/p>\n<p>Kub\u00ed\u010dkov\u00e1 B.<sup>1<\/sup>, Rychnov\u00e1 J.<sup>1<\/sup>, Dost\u00e1lov\u00e1 K.<sup>1<\/sup>, Vyhnalov\u00e1 K.<sup>1<\/sup>, Mr\u00e1zkov\u00e1 J.<sup>3<\/sup>, Mandys V.<sup>3<\/sup>, Wimmerov\u00e1 M.<sup>2<\/sup>, Stiborov\u00e1 M.<sup>1<\/sup>, Hodek P.<sup>1<\/sup><\/p>\n<p><sup>1 <\/sup>Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, Prague, Czech Republic; <sup>2 <\/sup>Department of Biochemistry, Faculty of Science, Masaryk University, Kamenice 753\/5, Brno, Czech Republic; <sup>3 <\/sup>Department of Pathology, Third Faculty of Medicine, Charles University, Rusk\u00e1&nbsp; 87, Prague, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-18<\/strong><\/td>\n<td width=\"732\">Feasibility of Direct Peptide Reactivity Assay (DPRA) in evaluation of sensitization potential of chemicals and mixtures<\/p>\n<p>Rucki M.<sup>1<\/sup>, B\u011blastov\u00e1 L.<sup>1,2<\/sup>, Vlkov\u00e1 A.<sup>1<\/sup>, Kejlov\u00e1 K.<sup>1<\/sup>, J\u00edrov\u00e1 D.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Centre of Toxicology and Health Safety, National Institute of Public Health, Prague, Czech Republic,<sup>2<\/sup>Faculty of Medicine and Dentistry, Palack\u00fd University, Olomouc, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"803\">\n<h4>&nbsp;<\/h4>\n<h4><strong>Metabolism of Xenobiotics<\/strong><\/h4>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-19<\/strong><\/td>\n<td width=\"732\">TYROSINE KINASES INHIBITORS VANDETANIB AND LENVATINIB INDUCE THE EXPRESSION OF CYTOCHROME P450 1A1 IN RATS IN VIVO<\/p>\n<p>Dra\u010d\u00ednsk\u00e1 H., Bar\u00e1\u010dkov\u00e1 P., Jel\u00ednkov\u00e1 S., Stiborov\u00e1 M.<\/p>\n<p>Department of Biochemistry, Faculty of Science, Charles University, Prague, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-20<\/strong><\/td>\n<td width=\"732\">IMPACT OF DIHYDROMYRICETIN ON ALCOHOL METABOLISM<\/p>\n<p>Hodek P.<sup>1<\/sup>, Skotnicov\u00e1 A.<sup>1<\/sup>, Hauptmanov\u00e1 G.<sup>1<\/sup>, Kutinov\u00e1-Canov\u00e1 N.<sup>2<\/sup>, Stiborov\u00e1 M.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Department of Biochemistry, Faculty of Science, Charles University, Prague, Czech Republic; <sup>2<\/sup>Institute of Pharmacology, 1<sup>st<\/sup> Faculty of Medicine, Charles University, Prague, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-21<\/strong><\/td>\n<td width=\"732\">Metabolism of tyrosine kinase inhibitor Cabozantinib by liver microsomes<\/p>\n<p>Indra R.<sup>1<\/sup>, Jurecka T.<sup>1<\/sup>, Vavrova K.<sup>1<\/sup>, Pompach&nbsp;P.<sup>1<\/sup>, Heger Z.<sup>2<\/sup>, Adam V.<sup>2<\/sup>, Stiborova M.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Department of Biochemistry, Faculty of Science, Charles University, Prague, Czech Republic <sup>2<\/sup>Department of Chemistry and Biochemistry, Laboratory of Metallomics and Nanotechnology, Mendel University in Brno, Brno, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-22<\/strong><\/td>\n<td width=\"732\">Interactions of tyrosine kinase inhibitors vandetanib, lenvatinib, and cabozantinib with ellipticine influence the ellipticine-DNA aduct formation in vitro and in vivo<\/p>\n<p>Stiborov\u00e1 M.<sup>1<\/sup>, Kol\u00e1rik M.<sup>1<\/sup>, Indra R.<sup>1<\/sup>, Adam V.<sup>2<\/sup>, Heger Z.<sup>2<\/sup>, Kope\u010dkov\u00e1 K<sup> 3<\/sup>, Eckschlager T.<sup>3<\/sup>, Schmeiser H.H.<sup>4<\/sup>, Arlt V.M.<sup>5<\/sup><\/p>\n<p><sup>1<\/sup>Department of biochemistry, Charles University, Albertov 6, 128 43 Prague 2; <sup>2<\/sup>Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, 61300 Brno; <sup>3<\/sup>Department of Pediatric Hematology and Oncology, and Department of Oncology, 2<sup>nd<\/sup> Medical Faculty, Charles University and University Hospital Motol, 150 06 Prague; <sup>4<\/sup>Division of Radiopharmaceutical Chemistry, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, German; <sup>5<\/sup>Analytical and Environmental Sciences Division, MRC-PHE Centre for Environment and Health, King\u2019s College London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-23<\/strong><\/td>\n<td width=\"732\">Bioactivation of the Carcinogen Aristolochic Acid I and II in SULT1B1-humanised mice<\/p>\n<p>Moserov\u00e1 M.<sup>1<\/sup>, Reed L.<sup>2<\/sup>, Stiborov\u00e1 M<sup>1<\/sup>, Arlt V.M.<sup>2<\/sup><\/p>\n<p><sup>1<\/sup>Department of biochemistry, Charles University, Albertov 6, 128 43 Prague 2, Czech Republic; <sup>2<\/sup>Analytical and Environmental Sciences Division, MRC-PHE Centre for Environment and Health, King\u2019s College London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-24<\/strong><\/td>\n<td width=\"732\">Identification of the enzymes metabolizing the inhibitor of tyrosine kinases lenvatinib<\/p>\n<p>Vavrov\u00e1 K.<sup>1<\/sup>, Indra R.<sup>1<\/sup>, Pompach P.<sup>1<\/sup>, Heger Z.<sup>1<\/sup>, Adam V.<sup>2<\/sup>, Eckschlager T.<sup>3<\/sup>, Kope\u010dkov\u00e1 K.<sup>3<\/sup>, Stiborov\u00e1 M.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 40 Prague&nbsp;2, Czech Republic; <sup>2<\/sup>Department of Chemistry and Biochemistry, Laboratory of Metallomics and Nanotechnology, Mendel University in Brno, Zemedelska 1, 61300 Brno, Czech Republic; <sup>3<\/sup>Department of Pediatric Hematology and Oncology, 2<sup>nd<\/sup> Medical Faculty, Charles University and University Hospital Motol, 150 06 Prague, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-25<\/strong><\/td>\n<td width=\"732\">INVOLVEMENT OF UGT ENZYMES IN FLAVONOLIGNAN METABOLISM<\/p>\n<p>Vrba J.<sup>1<\/sup>, Ln\u011bni\u010dkov\u00e1 K.<sup>1<\/sup>, Kosina P.<sup>1<\/sup>, Papou\u0161kov\u00e1 B.<sup>2<\/sup>, Ulrichov\u00e1 J.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palack\u00fd University, Olomouc, Czech Republic; <sup>2<\/sup>Regional Centre of Advanced Technologies and Materials, Department of Analytical Chemistry, Faculty of Science, Palack\u00fd University, Olomouc, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-26<\/strong><\/td>\n<td width=\"732\">Difference in cytochrome P450 expression and activities in liver microsomes after application of metronidazole. Comparison of control and germ-free mice<\/p>\n<p>Zemanova N.<sup>1<\/sup>, Anzenbacher P.<sup>2<\/sup>, Zapletalova I.<sup>2<\/sup>, Lnenickova K.<sup>1<\/sup>, Vavreckova M.<sup>1<\/sup>, Hermanova P.<sup>3<\/sup>, Hudcovic T.<sup>3<\/sup>, Kozakova H.<sup>3<\/sup>, Anzenbacherova E.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Department of Medical Chemistry and Biochemistry and <sup>2<\/sup>Departmenty of Pharmacology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic, <sup>3 <\/sup>Institute of Microbiology ASCR, Novy Hradek, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"803\">\n<h4>&nbsp;<\/h4>\n<h4><strong>Methods in Toxicology<\/strong><\/h4>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-27<\/strong><\/td>\n<td width=\"732\">OPTIMIZATION OF THE LYMPHOCYTE PROLIFERATION ASSAY IN RAINBOW TROUT (ONCORHYNCHUS MYKISS)<\/p>\n<p>Minarova H.<sup>1,2<\/sup>, Palikova M.<sup>1<\/sup>, Mares J.<sup>3<\/sup>, Syrova E.<sup>1,2<\/sup>, Blahova J.<sup>4<\/sup>, Faldyna M.<sup>2<\/sup>, Ondrackova P.<sup>2<\/sup><\/p>\n<p><sup>1<\/sup>University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Veterinary Hygiene and Ecology, Department of Ecology and Diseases of Game, Fish and Bees, Brno, Czech Republic; <sup>2<\/sup>Veterinary Research Institute, Department of Immunology, Brno, Czech Republic; <sup>3<\/sup>Mendel University in Brno, Faculty of AgriSciences, Department of Zoology, Fisheries, Hydrobiology and Apiculture, Brno, Czech Republic; <sup>4<\/sup>University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Veterinary Hygiene and Ecology, Department of Animal Protection, Welfare and Behaviour, Brno, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-28<\/strong><\/td>\n<td width=\"732\">The use of alternative methods to animal testing in frame of the REACH regulation<\/p>\n<p>Zatkova M.<sup>1<\/sup>, Balejikova J.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Ministry of Economy of the Slovak Republic, Centre for Chemical Substances and Preparations, Bratislava, Slovakia<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"803\">\n<h4>&nbsp;<\/h4>\n<h4><strong>Nanotoxicology<\/strong><\/h4>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-29<\/strong><\/td>\n<td width=\"732\">INVESTIGATION OF INTERACTIONS OF VANDETANIB WITH APOFERRITIN<\/p>\n<p>J\u00e1klov\u00e1 K.<sup>1<\/sup>, Indra R.<sup>1<\/sup>, Dost\u00e1lov\u00e1 S.<sup>2<\/sup>, Heger Z.<sup>2<\/sup>, Adam V.<sup>2<\/sup>, Stiborov\u00e1 M.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Department of Biochemistry, Faculty of Science, Charles University, Prague, Czech Republic; <sup>2<\/sup>Department of Chemistry and Biochemistry, Laboratory of Metallomics and Nanotechnology, Mendel University in Brno, Brno, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-30<\/strong><\/td>\n<td width=\"732\">ALTERATION OF VIABILITY AND FUNCTIONAL STATE OF GONADAL CELLS BY METAL NANOPARTICLES<\/p>\n<p>Scsukov\u00e1 S., Buj\u0148\u00e1kov\u00e1 Mlynar\u010d\u00edkov\u00e1 A.<\/p>\n<p>Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-31<\/strong><\/td>\n<td width=\"732\">Construction of nanoparticles bearing lenvatinib: theoretical and practical approaches<\/p>\n<p>Tak\u00e1csov\u00e1 P.<sup>1<\/sup>, Indra R.<sup>1<\/sup>, Heger Z.<sup>2<\/sup>, Adam V.<sup>2<\/sup>, Barv\u00edk I.<sup>3<\/sup>, Stiborov\u00e1 M.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Department of Biochemistry, Faculty of Science, Charles University, Prague, Czech Republic; <sup>2<\/sup>Department of Chemistry and Biochemistry, Laboratory of Metallomics and Nanotechnology, Mendel University in Brno, Brno, Czech Republic; <sup>3<\/sup>Division of Biomolecular Physics, Institute of Physics, Faculty of Mathematics and Physics, Charles University, Ke Karlovu 5, 121 16 Prague 2, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\">&nbsp;<\/td>\n<td width=\"732\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"803\">\n<h4>&nbsp;<\/h4>\n<h4><strong>Pharmacotoxicology<\/strong><\/h4>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-32<\/strong><\/td>\n<td width=\"732\">Synthesis of phenylethanoid glycopyranosides and their structure vs. activity assessment in cell-free tests and on human cells cutured in vitro<\/p>\n<p>Horv\u00e1thov\u00e1 E.<sup>1<\/sup>, Mastihubov\u00e1 M.<sup>2<\/sup>, Karni\u0161ov\u00e1 Potock\u00e1 E.<sup>2<\/sup>, Kis P.<sup>2<\/sup>, G\u00e1lov\u00e1 E.<sup>3<\/sup>, \u0160ev\u010dovi\u010dov\u00e1 A.<sup>3<\/sup>, Klap\u00e1kov\u00e1 M.<sup>3<\/sup>, Hun\u00e1kov\u00e1 \u013d.<sup> 1<\/sup>, Mastihuba V.<sup>2<\/sup><\/p>\n<p><sup>1 <\/sup>Cancer Research Institute BMC, University Science Park for Biomedicine, Slovak Academy of Sciences, Bratislava, Slovakia; <sup>2 <\/sup>Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia; <sup>3 <\/sup>Department of Genetics, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-33<\/strong><\/td>\n<td width=\"732\">Effect of venlafaxin treatment on metabolic risk factors and synaptic plasticity in hippocampus of rats with metabolic syndrome<\/p>\n<p>Mich\u00e1likov\u00e1 D.<sup>1,2<\/sup>, Sasv\u00e1riov\u00e1 M.<sup>3<\/sup>, \u0160v\u00edk K.<sup>1<\/sup>, Slov\u00e1k L.<sup>1<\/sup>, Tyukos Kaprinay B.<sup>1<\/sup>, Sotn\u00edkov\u00e1 R.<sup>1<\/sup>, Stankovi\u010dov\u00e1 T.<sup>3<\/sup>, G\u00e1sp\u00e1rov\u00e1 Z.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Slovak Academy of Sciences, Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Bratislava, Slovak Republic; <sup>2<\/sup>Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Martin, Slovak Republic; <sup>3<\/sup>Comenius University in Bratislava, Pharmaceutical Faculty, Bratislava, Slovak Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-34<\/strong><\/td>\n<td width=\"732\">The effect of microbiome on pharmacokinetics of drugs. Example of metronidazole.<\/p>\n<p>Anzenbacherova E. <sup>1<\/sup>, Zemanova N.<sup>1<\/sup>,&nbsp; Zapletalova I.<sup>2<\/sup>, Lnenickova K.<sup>1<\/sup>, Vavreckova M.<sup>1<\/sup>, Hermanova P.<sup>3<\/sup>, Hudcovic T.<sup>3<\/sup>, Kozakova H.<sup>3<\/sup>, Anzenbacher P.<sup>2<\/sup><\/p>\n<p><sup>1<\/sup>Department of Medical Chemistry and Biochemistry and <sup>2<\/sup>Departmenty of Pharmacology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic, <sup>3 <\/sup>Institute of Microbiology ASCR, Novy Hradek, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-35<\/strong><\/td>\n<td width=\"732\">EVALUATION OF THE REPRODUCTIVE TOXICITY OF TOPICAL MINOXIDIL IN LABORATORY FEMALE RATS<\/p>\n<p>Chemodurova N.<sup>1<\/sup>, Kuzminov B.<sup>1<\/sup>, Turkina&nbsp;V.<sup>1<\/sup>, Sklyarova H.<sup>2<\/sup>, \u041auzminov Y.<sup>3<\/sup><\/p>\n<p><sup>1<\/sup>\u0421entral research laboratory and laboratory of industrial toxicology; <sup>2<\/sup>Faculty of Postgraduate Education; <sup>3<\/sup>Department of Pediatrics, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-36<\/strong><\/td>\n<td width=\"732\">Effect of repeated administration of haloperidol and aripiprazol on behavioural outcomes in chronic mild stress model in rats<\/p>\n<p>Koprdova R.<sup>1<\/sup>, Osacka J.<sup>2<\/sup>, Kiss A.<sup>2<\/sup>, Mach M.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Institute of Experimental Pharmacology and Toxicology, Centre of Experimental Medicine, Slovak Academy of Sciences, Dubravska cesta 9, 841 04, Bratislava, Slovakia; <sup>2<\/sup>Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Dubravska Cesta 9, 84104, Bratislava, Slovakia<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-37<\/strong><\/td>\n<td width=\"732\">Anti-inflammatory activity of resveratrol and its prenylated derivative on paw edema model in mice<\/p>\n<p>Kuzm\u00ednov\u00e1 G.<sup>1<\/sup>, \u0160mejkal K.<sup>2<\/sup>, Klus\u00e1kov\u00e1 J.<sup>3<\/sup>, Kru\u017eicov\u00e1 A.<sup>1<\/sup>, Horsk\u00e1 K.<sup>1<\/sup>, Chalupov\u00e1 M.<sup>1<\/sup>, Ra\u010dansk\u00e1 E.<sup>4<\/sup>, Bob\u00e1l P.<sup>5<\/sup>, P\u00ed\u017eov\u00e1, H.<sup>5<\/sup>, Such\u00fd P.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Department of Human Pharmacology and Toxicology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic; <sup>2<\/sup>Department of Natural Drugs, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic; <sup>3<\/sup>MDgK spol. s&nbsp;r.o., Brno, Czech Republic; <sup>4<\/sup>Department of Pharmacology and Toxicology, Comenius University in Bratislava, Bratislava, Slovak Republic; <sup>5<\/sup>Department of Chemical Drugs, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-38<\/strong><\/td>\n<td width=\"732\">Effect of venlafaxine on the function of isolated rat heart modified by high-fat-fructose diet<\/p>\n<p>Salvaras, L.<sup>1<\/sup>, Knezl, V.<sup>2<\/sup>, Sasv\u00e1riov\u00e1, M.<sup>1<\/sup>, Mich\u00e1likov\u00e1, D.<sup>2<\/sup>, Tykos Kaprinay, B.<sup>2<\/sup>, G\u00e1sp\u00e1rov\u00e1, Z.<sup>2<\/sup>, Stankovi\u010dov\u00e1, T<sup> 1<\/sup>.<\/p>\n<p><sup>1<\/sup>Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic; <sup>2<\/sup>Institute of Experimental Pharmacology and Toxicology, Centre of Experimental Medicine, Slovak Academy of Sciences, Bratislava, Slovak Republic.<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-39<\/strong><\/td>\n<td width=\"732\">GENERAL TOXICITY ASSESSMENT OF THE NOVEL ALDOSE REDUCTASE INHIBITOR CEMTIRESTAT<\/p>\n<p>Soltesova Prnova M.<sup>1<\/sup>,&nbsp; Balekova J.<sup>1<\/sup>,&nbsp; Kovacikova L.<sup>1<\/sup>, Lomenova J.<sup> 1<\/sup>, Michalikova S.<sup> 1<\/sup>&nbsp; Rackova L.<sup>1<\/sup>, Karasu C.<sup>2<\/sup> ,&nbsp; Stefek, M.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Department of Biochemical Pharmacology, Institute of Experimental Pharmacology and Toxicology, CEM, Slovak Academy of Sciences, Dubravska cesta 9, 84104 Bratislava, Slovakia; <sup>2<\/sup>Department of Medical Pharmacology, Faculty of Medicine, Gazi University, 06510, Be\u015fevler, Ankara, Turkey<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-40<\/strong><\/td>\n<td width=\"732\">COMPARATIVE EFFECTS OF CEMTIRESTAT, STOBADINE AND EPALRESTAT ON GLUTATHIONE-S-TRANSFERASE AND CATALASE ACTIVITIES IN THE LIVER AND LUNG OF DIABETIC RATS GIVEN HIGH FRUCTOSE DIET AND STREPTOZOTOCIN<\/p>\n<p>Afandiyeva N <sup>1<\/sup>, Elmazoglu Z.<sup>2<\/sup>, Bek Aydin Z.<sup>2<\/sup>,&nbsp; Ceylan Asli F.<sup>3<\/sup>, Stefek M.<sup>4<\/sup>, Kavutcu M.<sup>1<\/sup>&nbsp; Karasu C.<sup>2<\/sup><\/p>\n<p><sup>1<\/sup>Gazi University, Faculty of Medicine, Department of Medical Biochemistry, Ankara, Turkey; <sup>2<\/sup>Gazi University, Faculty of Medicine, Department of Medical Pharmacology, Ankara, Turkey; <sup>&nbsp;3<\/sup>Ankara Yildirim Beyazit University, Faculty of Medicine, Department of Medical Pharmacology, Ankara, Turkey; <sup>4<\/sup>Slovak Academy of Sciences, CEM, Institute of Experimental Pharmacology and Toxicology, Bratislava, Slovakia<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-41<\/strong><\/td>\n<td width=\"732\">Pseurotins as potential cytostatics in human lymphomas<\/p>\n<p>Vasicek O.<sup>1,2<\/sup>, Mosejova E.<sup>1<\/sup>, Bosnjakovic R.<sup>1,3<\/sup>, Kubala L.<sup>1,2<\/sup><\/p>\n<p><sup>1<\/sup>Institute of Biophysics, Academy of Sciences of the Czech Republic, v. v. i., Brno, Czech Republic; <sup>2<\/sup>International Clinical Research Center \u2013 Centre of Biomolecular and Cellular Engineering, St. Anne\u2018s University Hospital, Brno, Czech Republic; <sup>3<\/sup>Department of Biology, Josip Juraj Strossmayer University of Osijek, Osijek, 31000, Croatia<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-42<\/strong><\/td>\n<td width=\"732\">Effect of Coenzyme Q10 and Different Varieties of Cornelian Cherry on Nitric Oxide Generation in the Heart and Aorta of Obese Zucker Rats<\/p>\n<p>Dayar E., Cebova M., Kosutova M., Pechanova O.<\/p>\n<p>Centre of Experimental Medicine, Slovak Academy of Sciences, Bratislava, Slovak Republic<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"803\">\n<h4>&nbsp;<\/h4>\n<h4><strong>Toxicology <em>In Vitro<\/em><\/strong><\/h4>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-43<\/strong><\/td>\n<td width=\"732\">Action of bisphenol analogs on porcine granulosa cells<\/p>\n<p>Buj\u0148\u00e1kov\u00e1 Mlynar\u010d\u00edkov\u00e1 A., Scsukov\u00e1 S.<\/p>\n<p>Institute of Experimental Endocrinology, Biomedical Research Center SAS, Bratislava, Slovakia<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-44<\/strong><\/td>\n<td width=\"732\">Bat liver cells: in vitro cytotoxicity of insecticides<\/p>\n<p>N\u011bmcov\u00e1 M.<sup>1<\/sup>, Kov\u00e1\u010dov\u00e1 V.<sup>1<\/sup>, Zukal J.<sup>2<\/sup>, Pikula J.<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>\u00dastav ekologie a chorob zv\u011b\u0159e, ryb a v\u010del, Veterin\u00e1rn\u00ed a farmaceutick\u00e1 univerzita Brno; <sup>2<\/sup>\u00dastav biologie obratlovc\u016f Akademie v\u011bd \u010cR, v. v. i., Brno<\/td>\n<\/tr>\n<tr>\n<td width=\"71\"><strong>P-45<\/strong><\/td>\n<td width=\"732\">INTERACTION OF NOVEL CDK INHIBITORS WITH HUMAN LIVER CYTOCHROMES P450<\/p>\n<p>\u0160pi\u010d\u00e1kov\u00e1 A.<sup>1<\/sup>, Kraus P.<sup>3<\/sup>, Strnad M.<sup>3<\/sup>, Anzenbacher P.<sup>1,2<\/sup><\/p>\n<p><sup>1<\/sup>Department of Pharmacology, Faculty of Medicine, Palack\u00fd University, Czech Republic; <sup>2<\/sup>Institute of&nbsp;Molecular and Translational Medicine, Faculty of Medicine, Palack\u00fd University, Czech Republic; <sup>3<\/sup>Laboratory of Growth Regulators, Faculty of Science, Palack\u00fd University, Czech Republic<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ecotoxicology P-1 ENVIRONMENTAL OCCURRENCE AND TOXICITY OF ORGANIC UV FILTERS Cahov\u00e1 J.1, Blahov\u00e1 J.1, Svobodov\u00e1 Z.1 1 Department of Animal Protection, Welfare and Behaviour, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno,&nbsp; Czech republic P-2 Aquatic ecosystems comparison from the point of view of heavy metals pollution Dvo\u0159\u00e1k P.1, <a class=\"read-more\" href=\"http:\/\/konferencia.uef.sav.sk\/?page_id=713\">Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/konferencia.uef.sav.sk\/index.php?rest_route=\/wp\/v2\/pages\/713"}],"collection":[{"href":"http:\/\/konferencia.uef.sav.sk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/konferencia.uef.sav.sk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/konferencia.uef.sav.sk\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/konferencia.uef.sav.sk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=713"}],"version-history":[{"count":4,"href":"http:\/\/konferencia.uef.sav.sk\/index.php?rest_route=\/wp\/v2\/pages\/713\/revisions"}],"predecessor-version":[{"id":722,"href":"http:\/\/konferencia.uef.sav.sk\/index.php?rest_route=\/wp\/v2\/pages\/713\/revisions\/722"}],"wp:attachment":[{"href":"http:\/\/konferencia.uef.sav.sk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=713"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}